CAR T cell - significado y definición. Qué es CAR T cell
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Qué (quién) es CAR T cell - definición


CAR T cell         
  • Depiction of adoptive cell transfer therapy with CAR-engineered T cells
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  • Different components of a chimeric antigen receptor
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ARTIFICIAL T-CELL RECEPTOR FOR USE IN IMMUNOTHERAPY
Chimeric T cell receptor; Artificial T cell receptors; Artificial t cell receptor; Artificial T cell receptor; Chimeric Antigen Receptor; CAR-T; Genetically engineered T cell; Engineered T-cell; Chimeric antibody receptor; CAR-T therapy; CAR T-cell therapy; CAR-T cell; CAR T cells; Chimeric antigen receptor; CAR-T Cell Therapy; CAR-T cells; Chimeric antigen receptor T cell; CAR T-cell
Chimeric antigen receptor T cells (also known as CAR T cells) are T cells that have been genetically engineered to produce an artificial T cell receptor for use in immunotherapy.
T-cell receptor         
  • Antigen presentation stimulates T cells to become either "cytotoxic" CD8+ cells or "helper" CD4+ cells.
MOLECULE FOUND ON THE SURFACE OF SOME IMMUNE CELLS
Alpha-beta T-cell antigen receptor; Genes, t-cell receptor; T-cell receptors; Receptors, antigen, t-cell; T-cell antigen receptors; TCRδ1; TCRd1; T cell receptor
The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively low affinity and is degenerate: that is, many TCRs recognize the same antigen peptide and many antigen peptides are recognized by the same TCR.
Naive T cell         
CELL TYPE
Naive T cells; Th0 cell; Naive t cell; Th0; T-helper zero; Naive T-cell; Naive T-cells; Naïve T cell; Naïve T cells
A naive T cell (Th0 cell) is a T cell that has differentiated in the thymus, and successfully undergone the positive and negative processes of central selection in the thymus. Among these are the naive forms of helper T cells (CD4+) and cytotoxic T cells (CD8+).